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Targets EGFR in NSCLC, SCCHN and other solid tumors
November 5, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
ImmunoGen has begun a Phase I trial of its EGFR-targeting antibody-drug conjugate (ADC), IMGN289. IMGN289 will be evaluated in a multi-center trial designed to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and anticancer activity of the compound, administered weekly, in patients with non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head and neck cancer (SCCHN), or other EGFR-positive solid tumors. Once its maximum tolerated dose is defined in the dose-fin...
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